Post-genome informatics - Minoru Kanehisa

The genome projects have now entered a rapid production phase with complete genome sequences and complete gene catalogues already available for a number of organisms and an increasing number expected shortly. In addition the new DNA and protein chip technologies can produce functional data about genes such as gene expression profiles at a rapid rate. There is therefore a large and ever increasing amount of data about genes and molecules. However there is still a hugegap between information at the molecular level and information at the level of integrated biological systems. It is this gap that is addressed in Post-genome Informatics.
Post-genome informatics is the analysis of biological functions in terms of the network of interacting molecules and genes withthe aim of understanding how a biological system is organized from its individual building blocks. As well as containing a comprehensive survey of the database and computational technologies relevant to molecular sequence analysis, Post-genome Informatics will provide the reader with a conceptual framework and practical methods for the representation and computation of molecular networks.

Professor Kanehisa is a Principal Investigator in the Genome Informatics Project in Japan. He speaks widely on the subject and is on the editorial board of the journal Bioinformatics.

"I would recommend this book to anyone as a very readable and relatively non-technical introduction to computational molecular biology" Statistical Methods in Medical Research

"As a whole the first three chapters would make a valuable basis for tutorial discussions for a final-year graduate students in Bioinformatics." Journal of Cell Science