High performance liquid chromatography in biotechnology - William S. Hancock

High Performance Liquid Chromatography in Biotechnology Edited by William S. Hancock This important book details the broad range of analytical techniques that have made HPLC so successful in the separation and quantitation of product variants–a procedure essential to quality assurance of protein pharmaceuticals. Outlined are the major chromatographic techniques–reversed phase, ion exchange, affinity and hydrophobic interaction chromatography–as well as their role in specific separations. Also described are the methods required for a quality control program. Reflecting the heightened concern for product integrity since the advent of new protein pharmaceuticals by recombinant–DNA techniques, this critical reference will enhance the libraries of analytical chemists, biochemists, and chemical engineers working with HPLC. 1990 (0–471–82584–0) 624 pp.