Sizeable new sections have been added to take account of recent theoretical and clinical developments, particularly in the chapters dealing with the dementias and toxic disorders, and in relation to the expanding range of rarer neurodegenerative disorders. The problems of HIV infection receive extensive coverage, also the accumulating evidence pointing towards a neuropsychiatric basis for schizophrenia. Advances in brain imaging are dealt with in detail, also salient discoveries in the fields of molecular biology and molecular genetics. In the course of the revision almost as many new references have been added as remain from the previous editions.
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